Understanding Your Treatment Options
For individuals struggling with treatment-resistant depression (TRD), PTSD, anxiety, or chronic pain, traditional antidepressants and therapy may not provide the relief they need. SPRAVATO® (esketamine) and IV ketamine therapy have emerged as groundbreaking options, but understanding their differences is essential in choosing the right treatment for your needs.
At Invictus Clinic in Marietta, GA, we specialize in both SPRAVATO® and IV ketamine therapy, helping patients achieve significant improvements in their mental health and well-being. Let’s explore how these treatments compare so you can make an informed decision.
What is SPRAVATO®?
SPRAVATO® is an FDA-approved nasal spray containing esketamine, a derivative of ketamine. It is specifically approved for treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal ideation. Unlike traditional antidepressants, which take weeks to work, SPRAVATO® provides rapid relief by targeting glutamate receptors to restore brain function.
What is IV Ketamine Therapy?
IV ketamine therapy involves the intravenous administration of racemic ketamine, which affects both glutamate and NMDA receptors. This treatment has been extensively studied for depression, PTSD, anxiety, bipolar disorder, and chronic pain conditions. It works by promoting neuroplasticity, helping the brain rebuild connections that improve mood and cognition.
SPRAVATO® vs. IV Ketamine: Key Differences
Both SPRAVATO® and IV ketamine have high success rates, but their administration, mechanism, and accessibility differ. Here’s how they compare:
1. Administration & Convenience
- SPRAVATO®: A nasal spray administered in a clinical setting under medical supervision. Requires patients to stay for two hours post-treatment for monitoring.
- IV Ketamine: Delivered via intravenous infusion in a controlled setting. Each session lasts 40-60 minutes, with post-monitoring as needed.
2. FDA Approval & Insurance Coverage
- SPRAVATO®: FDA-approved for treatment-resistant depression, making it more likely to be covered by insurance.
- IV Ketamine: Considered off-label for depression but widely used for various mental health and pain conditions. Insurance coverage is limited.
3. Speed of Effectiveness
- SPRAVATO®: Improvements typically seen within 2-6 weeks, requiring twice-weekly sessions at first.
- IV Ketamine: Rapid relief, often within hours to days, making it ideal for those experiencing severe depressive episodes or suicidal ideation.
4. Conditions Treated
- SPRAVATO®: Primarily for treatment-resistant depression (TRD) and MDD with suicidal ideation.
- IV Ketamine: Effective for depression, PTSD, anxiety, bipolar disorder, OCD, and chronic pain conditions.
5. Treatment Duration & Maintenance
- SPRAVATO®: Requires an ongoing schedule, typically twice per week for the first month, followed by weekly or biweekly maintenance sessions.
- IV Ketamine: Usually given as a series of six infusions over two to three weeks, with maintenance sessions as needed.
Who is a Good Candidate for Each Treatment?
- SPRAVATO® is best for:
- Individuals with treatment-resistant depression
- Patients seeking an FDA-approved option with insurance coverage
- Those comfortable with ongoing maintenance treatments
- IV Ketamine is best for:
- Those needing rapid relief from severe depression, anxiety, or PTSD
- Patients seeking off-label treatments for chronic pain or bipolar disorder
- Individuals who prefer shorter treatment cycles with less frequent maintenance
Side Effects & Safety Considerations
Both treatments are safe when administered by medical professionals, but they do have some side effects:
- SPRAVATO®:
- Temporary dizziness, nausea, and dissociation
- Possible increase in blood pressure
- Requires a two-hour monitoring period after administration
- IV Ketamine:
- Mild hallucinogenic or dissociative effects, which wear off quickly
- Potential nausea or dizziness, often managed with supportive care
- Shorter post-treatment recovery compared to SPRAVATO®
Why Choose Invictus Clinic in Marietta, GA?
At Invictus Clinic, we provide expert guidance and personalized treatment plans to help patients find the best solution for their mental health and chronic pain needs. Our approach includes:
- Comprehensive Evaluations: Determining whether SPRAVATO® or IV ketamine is right for you.
- A Comfortable, Safe Setting: Experienced professionals oversee all treatments to ensure safety and effectiveness.
- Insurance & Financing Assistance: We help patients navigate insurance coverage for SPRAVATO® and explore options for IV ketamine.
Take the Next Step Toward Healing
Choosing the right treatment for depression, anxiety, PTSD, or chronic pain can be life-changing. If you’re unsure whether SPRAVATO® or IV ketamine therapy is the best fit for you, our team at Invictus Clinic in Marietta, GA is here to help.
📍 Contact Invictus Clinic today to schedule a consultation and start your journey to lasting relief.
🔗 Visit our website to learn more!
📞 Call us at 770-580-1042 to book an appointment.
